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Curriculum vitae

Professor 1996; President of the Republic of Poland
D.Sc. (habilitation) 1989; Isotope effects on kinetically complex reactions; Department of Chemistry, Technical University of Łódź, Poland
Ph.D. 1984 (with honors); Oxygen and sulfur kinetic isotope effects on thermal isomerization of bis(5,5-dimethyl-1,3,2,-dioxaphosphorinanyl); advisor prof. dr. W Reimschüssel; Department of Chemistry, Technical University of Łódź, Poland
M.S. 1976 (with honors); Oxygen kinetic isotope effect on isomerization of monothiopyrophosphates; advisor prof. dr. W Reimschüssel; Department of Chemistry, Technical University of Łódź, Poland

Publications

  • “RNA-Inspired and Accelerated Degradation of Polylactide in Seawater” Rheinberger, Timo; Wolfs, Jonas; Paneth, Agata; Gojzewski, Hubert; Paneth, Piotr; Wurm, Frederik J. Am. Chem. Soc. 143, 16673-16681 (2021)
  • “Precision Biotransformation of Emerging Pollutants by Human Cytochrome P450 using Computational-Experimental Synergy: A Case Study of Tris(1,3-dichloro-2-propyl) Phosphate” Chai, Lihong; Zhang, Huanni; Song, Runqian; Yang, Haohan; Yu, Haiying; Paneth, Piotr; Kepp, Kasper; Akamatsu, Miki; Ji, Li Environ. Sci. Technol. 55, 14037-14050 (2021)
  • “Machine Learning augmented docking studies of aminothioureas at the SARS-CoV-2 – ACE2 interface” Monika Rola, Jakub Krassowski, Julita Górska, Anna Grobelna, Wojciech Płonka, Agata Paneth, Piotr Paneth PLoS One 16, e0256834 (2021)
  • “4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-Toxoplasma gondii agents” Adrian Bekier, Lidia Węglińska, Piotr Paneth, Agata Paneth, Katarzyna Dzitko J. Enz. Inhib. Med. Chem. 36, 1145-1164 (2021)
  • “1,3,4-Thiadiazoles effectively block invasion and inhibit proliferation of Toxoplasma gondii” Lidia Węglińska, Adrian Bekier, Katarzyna Dzitko, Barbara Pacholczyk-Sienicka, Łukasz Albrecht, Tomasz Plech, Piotr Paneth, Agata Paneth Cells 10, 2053 (2021)
  • “New organometallic ruthenium(II) complexes with purine analogs – a wide perspective on their biological application” Marzena Fandzloch, Tomasz Jędrzejewski, Liliana Dobrzańska, Ginés M. Esteban-Parra, Joanna Wiśniewska, Agata Paneth, Piotr Paneth and Jerzy Sitkowski Dalton Trans. 50, 5557 (2021)

ISOEFF

Program Isoeff allows to calculate values of isotope effects based on the Bigeleisen equation from quantum-chemical results. Currently results from the following packets are supported: Gaussian, Gamess, Charmm and Mopac. Isoeff can also be used for studies of the influence of small changes of individual elements of Hessian matrix on resulting value of isotope effect.

Current support

Current support / Institutional
  • “International Centre for Research on Innovative Biobased Materials” (ICRI-BioM), Teaming for Excellence, Horizon2020, local coordinator
Current support / Personal
  • “International Centre for Research on Innovative Biobased Materials – ICRI-BioM (International Research Agenda), Teaming for Excellence, Horizon2020, Foundation for Polish Science, MAB PLUS/2019/11 (2019-2023)
  • “Binding isotope effects as a new, unique tool for studies of receptor – ligand interactions”, NCN 2011/02/A/ST4/00246 (2012-2017) (Maestro), PI
  • “Novel stable isotope-based approaches for assessing the biodegradation of soil and groundwater contaminants”, PSRP-025/2010 (2011-2016), PI
  • “Convention de cotutelle internationale de these, Agreement for international joint doctorate supervision (cotutelle)” for Katarzyna Romek – French goverment (2013-2017), scientific advisor
  • „Searching for improved bioactivity of azole-based metallo-drugs” MNiSW, China-Poland Scientific and Technological Cooperation, grant P# 36-34 (2015-2017), PI

Innovations

International patents
  • “N-Triazynylammonium salts, a method of preparation and uses thereof” European submission EPO nr. 10195135.8-2101 from 07.03.2011 with priority PL/14.07.10/PLA 39183210, European patent awarded: 2407460B1 17.07.2013
Polish patents
  • „Sposób autentykacji kawy” Ewelina Kosiacka, Piotr Paneth, pending patent nr P.396939 of 10.11.2011, awarded: PAT.220057 16.12.2014
  • “Pochodne 1,2,4-triazolo-5-tionu oraz ich zastosowanie” Tomasz Frączek, Agata Siwek, Piotr Paneth pending patent P.401956 of 10.12.2012, published PAT.221213 on 23.6.2014
  • „Nowa pochodna 1,4-dipodstawionego tiosemikarbazydu, sposób jej wytwarzania oraz inhibicja bakteryjnej topoizomerazy IV” A. Siwek, P. Paneth, P. Stączek, J. Stefańska, pending patent nr P.390774 z dnia 20.03.2010, awarded: PAT.212639 19.04.2012
  • “Sposób przygotowania próbki chlorku srebra przeznaczonej do badania składu izotopowego chloru w spektrometrach mas z jonizacją FAB lub SIMS” R. Kamiński, P. Paneth, pending patent nr P.388338 z dnia 22.06.2009)  awarded: PAT.212330 02.04.2012

Courses based on research (RBL)

  • 2015: within molecular modeling course for PhD candidates studies of preferential binding of metal cations by centers embedded in polymers are carried out .
  • 2008: within computational chemistry laboratory for students of the 4th year the dependence of kinetic isotope effects on the mechanism of dehalogenation reaction has been studied. Results were published in Journal of Chemical Theory and Computations (IF2014 = 5.50) published by the Americal Chemical Society:"A DFT study of the kinetic isotope effects on the competing SN2 and E2 reactions between hypochlorite anion and ethyl chloride" A. Pabis, P. Paluch, J. Szala, P. Paneth, J. Chem. Theory Comput. 5, 33-36 (2009)